The existence of all major international organizations in Geneva has also made the city the essential for global NGOs working within the international organization system. As a result, most major NGOs working across fields such as trade and development, health, human rights, environment, and education, are present in Geneva.

Geneva, or its vicinity, also serves as the headquarters of major international NGOs, in particular the World Economic Forum, World Wide Fund for Nature, Terre des Hommes, and the World Conservation Union (to name but a few). Major foundations and funds are also established in Geneva, such as the Aga Khan Foundation and the Global Fund.

An exhaustive list of IOs and NGOs organizations in Geneva is provided by the following resources:

* Geneva Economic Development Office
* The Briefing Book on International Organizations in Geneva

Aga Khan Foundation
Airports Council International (ACI)
Amnesty International 
Anti-Racism information Service (ARIS)
Association for the Prevention of Torture (APT)
Bellerive Foundation
Center for International Environmental Law (CIEL)
Defence for Children international (DCI) 
Development Innovations and networks (IRED)
Doctors Without Borders - Medecins Sans Frontieres (MSF)
Geneva Center for Security Policy (GCSP) 
Geneva Humanitarian Forum (GHF) 
Geneva International Centre for Humanitarian Demining (GICHD) 
Geneva International Peace Research Institute
Global Alliance for Vaccines and Immunization
Green Cross International
Handicap International  (Suisse) 
Human Rights Information and Documentation System (HURIDOCS)
Indigenous People's Center for Documentation, Research and Information (doCip)
International Bureau of Education (IBE)
International Centre for Trade and Sustainable Development (ICTSD)
International Civil Defense Organization
International Commission of Jurists
International Commission of Jurists (ICJ)
International Confederation of Free Trade Unions (ICFTU)
International Council of Nurses
International Council of Voluntary Agencies
International Council of Voluntary Agencies (ICVA) 
International Council on Human Rights Policy (ICHRP)
International Federation Terre des Hommes (IFTDH) 
International Institute for Sustainable Development (IISD)
International Institute of Humanitarian Law 
International Organisation of Employers (IOE)
International Peace Bureau (IPB)
International Service for Human Rights (ISHR) 
International Social Security Association (ISSA)
International Union Against Cancer (UICC)
IUCN - The World Conservation Union
Mandat International
Migrants rights international (MRI) 
Pugwash Conferences
South Centre
The Association for Human Resource Management in International Organizations (AHRMIO)
The Geneva Centre for the Democratic Control of Armed Forces (DCAF)
The Global Fund to Fight AIDS, Tuberculosis and Malaria
United Nations Watch
World Business Council for Sustainable Development
World Economic Forum
World Federation of United Nations Associations (WFUNA)
World Organisation against Torture (OMCT) 
World Organization of the Scout Movement (WOSM)
World Wide Fund for Nature (WWF International)